Homeless and Addiction Recovery Treatment Hubs HART Hubs: Reference Document, January 2025

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One unsurprising consequence is that it gives consumers unprecedented ease of access to illicit—and oftentimes mysterious—substances. Each year, somewhere around a quarter to a third of GDS respondents say that they’ve consumed a wider range of drugs since using the dark web. The breadth of the darknet’s product offering, combined with the relatively low barrier to entry, creates gateways to novel drug-using drughub.su behaviours, where people try new substances just because they’ve suddenly been made available to them. Drugshub.su serves as a dynamic link generator, providing short-term access in the event the principal links are not accessible. Learn how we’re keeping our communities safer and improving access to mental health through the transition of nine supervised drug injection sites into HART Hubs.

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Only quality sellers who meet our standards are approved to ensure buyer safety. Withdrawals are processed securely with multiple verification steps toensure fund safety and prevent unauthorized access. If issues arise, buyers have 3 days after escrow period to open disputes. Ourexperienced moderation team reviews all cases within 3-7 days, ensuring fairresolution based on evidence and platform policies.

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is the regularization term, which is the L1-norm.

• In our study, we found that 23.78% (9896/41,614) listings and traces were identified with the help of 58 opioid jargons (Table 2).
• That gap also worries advocates who are imploring Premier Ford to change his mind about closing down supervised consumption sites, warning drug problems will become more visible and more fatal — even with new funding — if he does not.
• Revolutionizes pre-clinical and clinical drug development through its cutting-edge organoid technology, enhancing its accuracy and efficiency.
• The suspects, all of whom have prior records, have been referred to the prosecutor.
• Key trends include automation, digital integration, smart systems, and innovation-led product development.
• This section elaborates on the methodology used to identify opioid trading information in the anonymous market and forums.
• Ultimately, Hub Services are indispensable in bridging the gap between patients and the life-saving therapies they require.
• In this way, we generated a rich underground marketplace opioid vocabulary of 311 opioid keywords with 13 categories.

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Through their numerous services, the hub acts to assist the patient in their health care journey. In relation to this idea, manufacturers are using hubs to shorten the supply chain, using logistics organizations to manage inventory and supply to appropriate pharmacies. This management can be in the form of a partner pharmacy that works explicitly with the manufacturer or a network of pharmacies that are contracted to dispense the manufacturer’s medication. Furthermore, many hubs may administrate quick start programs that are designed to provide patients with therapy while the benefits investigation is being resolved. Boiled down to the basics, a hub is a service that allows a manufacturer to have a singular point of contact with patients who utilize their therapies.

Vendors

Mayor Ellis said just over 200 people struggling with homelessness have been identified in his town, with the HART hubs likely to bring an average of 20 to 30 beds per location. Aerosols, nitrous, butane gas, and other household products – can they get you arrested? Ketamine can provide an out-of-body experience, but be careful where, when and how you use it.

Experienced Vendors

The focus remains on enhancing treatment accessibility and integrating advanced therapies, positioning Bangladesh as an emerging market for pancreatic and bile duct cancer management in South Asia. Sri Lanka’s pancreatic and bile duct cancer drug market is expected to grow steadily, supported by increased healthcare spending and improved diagnostic capabilities. Rising awareness about cancer symptoms and early detection programs are crucial factors. The government’s focus on expanding cancer treatment centers and facilitating access to modern therapeutics are fostering market development. The presence of international pharmaceutical companies and ongoing research collaborations further enhance treatment options. As the healthcare system continues to evolve, Sri Lanka is positioning itself as a key player in regional cancer management, with an emphasis on innovative therapies and patient-centric care models.

Security Features

Hub services act to simplify the complexity and perform as an intermediary between involved parties. The seized drugs include over 569 pounds of amphetamines, 95 pounds of cocaine, 95 pounds of MDMA and over 22 pounds of LSD and ecstasy pills, the agency said. Among them is Amgen, which in April announced a $900 million expansion of its Ohio manufacturing facility as part of a $1.4 billion investment plan it said has created 750 jobs. In addition, J&J kicked off 2026 by announcing plans to build a next-generation cell therapy manufacturing site in Pennsylvania.

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Our experiment evaluated MALLET on our annotated anonymous marketplace and forum data set (Table 3) using 3 classification algorithms in the document classification tool (package cc.mallet.classify class in MALLET’s JavaDoc API [Application Programming Interface]). In particular, MALLET is retrained and evaluated via 10-fold cross-validation. We also applied the MALLET topic modeling toolkit (package cc.mallet.topics MALLET’s class in JavaDoc API) on the same data set to predict the type of topic.

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Note that we should not overestimate the number of suppliers and buyers given the number of IDs found in this research, but we regarded it as the upper-bounded number of the opioid suppliers and buyers. This is because the same user could have different IDs, and the same ID in different marketplaces can point to different users. Owing to the anonymity of the underground marketplaces and forums, there exists no ground truth to link users with their IDs. The Drug Hub editorial team is made up of people who use(d) drugs, students, researchers, and healthcare professionals who work with marginalized and criminalized communities.

The Ministry of Health works to help people stay healthy, delivering high-quality care when they need it and protecting the health system for future generations. If canary is not updated or signature fails verification, assume compromise. Drug Hub operates a private Jabber server for push notifications and optional vendor communication. Jabber details are provided in your account settings after registration. Configure your Jabber client with provided credentials to receive instant alerts. Admin key is used for signing official announcements, canary files, and critical security notices.

Nineteen new addiction treatment hubs will be operational in Ontario before 10 supervised consumption sites are forced to close their doors in March, the Ford government is promising. Hopefully, this has helped to illuminate some of the mystery behind hubs and show how they work to ease the specialty process for some patients. Hub services are most often created for medications that have a complicated path into the patient’s hands. Finally, hub services exist to provide patients, providers, and pharmacies with visibility to co-pay assistance programs.

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Finally, we used natural language processing techniques to extract opioid trading information to characterize underground opioid commodities, suppliers, and transactions. In total, we collected 248,359 listings from 10 anonymous online marketplaces and 1,138,961 traces (ie, threads of posts) from 6 underground forums. As observed in our data set, the top 3 marketplaces with the most opioid listings are Agora, Evolution, and Apollon. Our research collected product listings and forum posts from 10 anonymous online market places and 6 forums. Our study determined the underground marketplace and forum list based on darknet site search engines and previous research works [20]. More specifically, we used darknet site search engines (such as Recon, Darknet live, Dark Eye, dark.fail, and DNStats [21,22]) to search underground marketplaces and forums and then manually validated their activeness.

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Integrated private Jabber server provides instant notifications for critical events. Administered by seasoned experts, pen-tested by top security specialists,with industry-leading protections like END GAME DDoS filter. All communications and sensitive data are protected using Pretty GoodPrivacy (PGP) encryption with 4096-bit keys, ensuring complete privacy fromthird-party interception.

Author Johann Hari explains in just two minutes something that has been argued over for years. Professor Winstock explains the questions doctors ask about alcohol, why they ask them, and how seeing your GP can help. Pills sold as diazepam can contain much more potentially dangerous drugs like bromazolam.

• First Logevity Limited provides a service to strictly match groups or individuals seeking investment capital with individuals looking to invest.
• Preparing amphetamine for injection changes it from a Class B to a Class A drug.
• In the above objective function, C+ is always larger than C−, which means that the penalty of misclassifying a positive instance is larger than that of a negative instance.
• Once the item is received, the buyer finalizes the purchase by notifying the anonymous online marketplace to release the funds held in escrow (step 11) [8,9].
• Hub services work closely with companies who are able to automate this process and can expedite the prior authorization process from weeks to days.
• As understanding of them improves, it is easy to see how they can benefit all stakeholders, including manufacturers, wholesalers, distributors, doctors, pharmacies, and patients.
• GSK announced plans in September to build an additional new biologics flex factory at Upper Merion focused on medicines for respiratory disease and cancer, with construction planned to start this year.
• When interpreted by professionals, our initial results demonstrate useful findings and may be used downstream by law enforcement and public policy makers for impactful structural interventions to the opioid crisis.
• In addition, we did not observe big changes in the top opioid commodity origins from 2014 to 2020.

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But another worrying knock-on effect is that people who buy drugs off the darknet, rather than through a contact or a friend, may be using those drugs alone. In 2017, Dr Barratt sought to find out why it was that Scandinavian countries like Finland consistently reported the world’s highest proportion of drug buyers who were using the dark web to purchase their supply. A local source explained that, due in part to the climate and the prohibitively cold weather, Finnish people are typically “more isolated” than other peoples around the world and “tend to stay home”. To ensure maximum stability and accessibility, each user is issued a private mirror, which is almost unique and can be accessed in the account settings. It is a priority for CBC to create products that are accessible to all in Canada including people with visual, hearing, motor and cognitive challenges. Jones has repeatedly rejected the suggestion that drug users could die as a result of a shift toward an abstinence-based treatment model.

That same report concluded the health ministry did not provide a thorough, evidence-based business case for the hub model and did not provide proper impact analysis or do proper consultations with all affected people. Harm reduction advocates have condemned the move to shutter supervised consumption sites, saying it will put lives at risk and only move drug use into public spaces. More than 2,600 Ontarians died in 2023 due to overdoses, the vast majority due to opioid toxicity. Supervised consumption sites impacted by the bill were given an option to apply to become HART hubs, and the nine facilities approved by the province will transition to the new model of care by March 31, the date they were slated to shut down. For example, there might be varying types of heroin or fentanyl, but we could not subcategorize them due to the lack of precise ontology. Addressing this challenge requires deep domain knowledge and expertise, which is constantly evolving.

In the highly competitive and precarious world of darknet marketplaces, such decisions can be the difference between thriving and imploding. Our modification of the semantic comparison model will generate comparable word embeddings for opioid jargon words in legitimate documents (ie, benign corpora embedding) and in underground corpora (ie, underground corpora embedding). Specifically, our modification used a series of opioid keywords collected to generate their benign corpora embeddings and then searched for words whose underground corpora embeddings were close to the opioid keywords’ benign corpora embeddings. We output the top 100 proper nouns in the underground corpora in our implementation, whose embeddings showed the closest cosine distance to the known opioid keywords. Longevity biotech Juvenescence today announced the first close of its Series B-1 financing round, securing $76 million to support the continued development of its AI-driven clinical pipeline focused on age-related diseases. The round was led by M42, a tech-enabled healthcare company headquartered in Abu Dhabi, with additional participation from existing investors.

Mackey et al [13] collected tweets related to the opioid topic to identify illicit online pharmacies and study the illegal sale of opioids in online marketing. Cherian et al [12] gathered codeine misuse data from Instagram posts to understand how misuse is happening and its misused form. However, to the best of our knowledge, no large-scale study, which may cross multiple anonymous marketplaces and is cross-sectional, has been conducted to profile the opioid supply chain and unveil characteristics of opioid suppliers, commodities, and transactions. This paper seeks to complement current studies widening the understanding of opioid supply chains in underground marketplaces using comprehensive, large-scale, longitudinal anonymous marketplace and forum data. To this end, we propose a series of techniques to collect data; identify opioid jargon terms used in the anonymous marketplaces and forums; and profile the opioid commodities, suppliers, and transactions.

Anonymous online marketplaces are usually platforms for sellers and buyers to conduct transactions in a virtual environment. They usually come with anonymous forums for sellers and buyers to share information, promote their products, leave feedback, and share experiences about purchases. To understand how it works, we describe an opioid transaction’s operational steps on the anonymous online marketplaces and forums. We present a view about how such services operate and how different entities interact with each other (Figure 1). The market for pancreatic and bile duct cancer drugs in Bangladesh is set to expand, driven by increasing disease prevalence and ongoing healthcare reforms.

However, the views, interpretations and conclusions set out in this publication are those of the author and are not necessarily those of the EMCDDA, Europol or their partners, any EU Member State or any agency or institution of the European Union. The agency, based in The Hague, built intelligence based on evidence from Germany, which it said seized the marketplace’s “criminal infrastructure” in December 2021. Europol said that 288 suspects were arrested and more than 50.8 million euros ($53.4 million) in cash and virtual currencies, 850 kilograms of drugs and 117 firearms were seized in a series of raids in several countries. Applications for the remaining 10 hubs are under review and will be announced in the coming weeks, the province said in the release, adding the goal is to have the facilities up and running by April 1. From a seemingly innocuous logo to systemic vulnerabilities, DrugHub’s downfall is a testament to the importance of vigilance in the digital age. It is a story that blends technical intrigue with the high stakes of the darknet, offering a glimpse into a world where even the smallest mistake can have monumental consequences.

This model employed a neural network–based embedding technique to analyze the semantics of words in different corpora. In particular, in the semantic comparison model, the size of the input layer was doubled while not expanding either the hidden or the output layer. Hence, every word has 2 vectors, each describing the word’s relations with other words in one corpus. In the meantime, these 2 vectors are still comparable because they are used together in the neural network to train a single skip-gram model for predicting the surrounding windows of context words. We trained the semantic comparison model using the traces of Reddit as the benign corpora and the traces of the anonymous marketplaces/forums as the underground corpora.

HUB Organoids (HUB) is the global leader in the field of adult stem cell-derived organoids. HUB Organoid Technology represents a paradigm shift for drug discovery and development, preclinical patient stratification, predictive diagnostics, personalized medicine, clinical trials, regenerative medicine, and companion diagnostics. HUB offers licenses to its proprietary technology and provides drug development services using its living organoid biobanks. Never access Drug Hub or any darknet marketplace without proper security precautions. Always use Tor Browser with security level set to “Safest.” Encrypt all sensitive communications with PGP.